The study aimed to evaluate the efficacy and safety of drug coated balloon-only strategy (DCB-only) in the treatment of de novo left main coronary artery (LM) bifurcation lesions.85 patients were enrolled in this study and classified them into two groups: DCB-only group (n = 36) and DES group (n = 49).The MLD of target vessels oakley fives 4.0 was measured before and immediately after percutaneous coronary intervention (PCI) and late luminal loss (LLL) were also calculated.And the occurrence of major adverse cardiovascular events (MACE) was also evaluated.Compared with that before PCI, the MLD of target lesions significantly increased immediately model 1840 light artillery saber after PCI ( P.
05).The use of DCB-only to treat de novo LM bifurcation lesions is effective and relatively safe, which provides new ideas for the treatment of LM coronary artery bifurcation lesions in the future.